产品货号：
Z36873
中文名称：
Huntingtin/HTT抗体
英文名称：
Anti-Huntingtin/HTT Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-Huntingtin/HTT Antibody |
| 指标别名 | HD;HD protein;HTT;huntingtin;Huntington disease protein;IT15 |
| 克隆性 | Monoclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB |
| 基因名称 | HTT |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthesized peptide derived from human Huntingtin May play a role in microtubule-mediated transport or vesicle function. |
| 实际分子量 | 348KD |
| 成分 | 500μg/mL;Rabbit IgG in phosphate buffered saline,pH7.4,150mM NaCl,0.02% sodium azide and 50% glycerol. |
| 纯化方式 | Affinity-chromatography |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | The huntingtin gene,also called HTT or HD(Huntington disease) gene,is the IT15("interesting transcript 15") gene which codes for a protein called the huntingtin protein.It is mapped to 4p16.3.The protein has no sequence homology with other proteins and is highly expressed in neurons and tests in humans and rodents.HTT upregulates the expression of Brain Derived Neurotrophic Factor(BDNF) at the transcription level,and this gene is required for normal development.The HTT protein is involved in vesicle trafficking as it interacts with HIP1,a clathrin-binding protein,to mediate endocytosis,the absorption of materials into a cell.HTT was also visualized as punctate staining likely to represent nerve endings.What's more,wildtype HTT may function in the nucleus in the assembly of nuclear matrix-bound protein complexes involved with transcriptional repression and RNA processing. |
| Uniprot ID | P42858 |
| 推荐稀释比 | Western blot (WB) 1:500～2000 |
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